Assignment Prompt & Instructions
– ## week2casestudywinter25studentversion.pdf
– ## INSTRUCTIONSFORCASESTUDY.docx
**## week2casestudywinter25studentversion.pdf**
Case Study Week 2
Patient Profile
• Name: Sarah L., 32-year-old female
• Occupation: Teacher
• Chief Complaint: “My skin rash keeps getting worse and is really itchy.”
• Onset: 2 weeks
• Past Medical History: Mild seasonal allergies, no chronic illnesses
• Medications: None
• Social History: Lives with two cats, recently moved into an older home; no recent
travel
• Family History: Mother—eczema; father—type 2 diabetes
History of Present Illness
The patient reports a progressively worsening itchy rash on the palms, elbows, and
behind the knees. Initially mild, the rash is now erythematous, dry, and starting to crack.
She notes increased itching at night.
Denies new soaps or detergents, but admits to using a new scented body lotion. Stress
levels have been high due to work.
Physical Examination
• Vitals:
o Temp 98.4°F
o HR 78 bpm
o BP 118/72 mmHg
o RR 14
• Skin Exam:
o Erythematous plaques with silver-white scale on elbows
o Lichenification in popliteal and antecubital fossae
o Small fissures on palmar surfaces
o No drainage, no signs of infection
• Nails:
o Mild pitting on fingernails
• Other Systems: Normal
Sample Lab Studies
Note: Skin disorders are often clinical diagnoses, but labs help rule out infection/allergy or
support alternatives.
CBC
Test Result Normal Range
WBC 7.0 x10³/µL 4.5–11
Hemoglobin 13.4 g/dL 12–16
Platelets 280 x10³/µL 150–400
Eosinophils 7% (high) 0–5
ESR
Test Result Normal
ESR 18 mm/hr 0–20 mm/hr
CRP
Test Result Normal
CRP 0.9 mg/dL <1
IgE Level
Test Result Normal
IgE 250 IU/mL 0–100 IU/mL
Skin Scraping (KOH prep)
• Negative for hyphae
**## INSTRUCTIONSFORCASESTUDY.docx**
INSTRUCTIONS FOR CASE STUDY
An understanding of cells and cell behavior is a critically important component of disease diagnosis and treatment. But some diseases can be complex in nature, with a variety of factors and circumstances impacting their emergence and severity.
Effective disease analysis often requires an understanding that goes beyond isolated cell behavior. Genes, the environments in which cell processes operate, the impact of patient characteristics, and racial and ethnic variables all can have an important impact.
An understanding of the signals and symptoms of alterations in cellular processes is a critical step in the diagnosis and treatment of many diseases. For APRNs, this understanding can also help educate patients and guide them through their treatment plans.
In this Assignment, you examine a case study and analyze the symptoms presented. In 1-2 pages, you will answer the questions provided following the case scenario. You must use current evidence-based resources to support your answers. Follow APA guidelines. Follow the grading rubric.
**To prepare:**
By Day 1 of this week, you will be assigned to a specific case study for this Case Study Assignment. Please see the “Announcements” section of the classroom for your assignment from your Instructor.
**The Assignment**
Develop a 1- to 2-page case study analysis by answering the questions provided following the case scenario.
**Case Study**
Ensure that you follow the rubric closely. When the rubric calls for current, evidence-based sources, this means that they should be within the last 5 years. You should have at least 2 sources cited. The textbook does not count as one of the sources. The prompt is attached as a pdf.
The following should be addressed in your 1-2 pages –
1. Describe the pathophysiology and reason for symptoms.
2. Discuss genetic mutations and risk factors associated with this disorder.
3. Identify racial/ethnic factors that can put patients more at risk. Discuss anything in the patient hx or lifestyle that would increase the potential for the disease process.
Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The sample paper provided at the Walden Writing Center provides an example of those required elements (available at
[https://academicguides.waldenu.edu/writingcenter/templatesLinks to an external site.](https://academicguides.waldenu.edu/writingcenter/templates)). All papers submitted must use this formatting.
| | | |
| — | — | — |
| Develop a 1- to 2-page case study analysis, examining the patient signs and symptoms presented in the case study; discussing the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. | **30 to >27.0 ptsExcellent** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. … The response is supported by evidence and/or research, as appropriate, to support the explanation.<br> <br>**27 to >24.0 ptsGood** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. … The response supported by evidence and/or research, as appropriate, to support the explanation.<br> <br>**24 to >22.0 ptsFair** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis in a manner that is vague or inaccurate. … The response is supported with explanations that are vague or based on inappropriate evidence/research.<br> <br>**22 to >0 ptsPoor** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis in a manner that is vague and inaccurate, or the description is missing. … The response does not include rationales, or the explanations are vague or based on inappropriate or no evidence/research. | 30 pts |
| This criterion is linked to a Learning OutcomeWhat role do genetic mutations play in the development of the disease? | **25 to >22.0 ptsExcellent** The response includes an accurate, complete, detailed, and specific analysis of the genes that may be associated with the development of the disease.<br> <br>**22 to >19.0 ptsGood** The response includes an accurate analysis of the genes that may be associated with the development of the disease.<br> <br>**19 to >17.0 ptsFair** The response includes a vague or inaccurate analysis of the genes that may be associated with the development of the disease.<br> <br>**17 to >0 ptsPoor** The response includes a vague or inaccurate analysis of the genes that may be associated with the development of the disease is missing. | 25 pts |
| This criterion is linked to a Learning OutcomeWhat is the impact of the disease on the immune system? …… How do treatment strategies target the pathophysiological mechanisms of the disease? | **30 to >27.0 ptsExcellent** The response includes an accurate, complete, detailed, and specific explanation of the impact of the disease on the immune system. Response includes an accurate, complete, detailed, and specific explanation of how treatment strategies target the pathophysiological mechanisms of the disease.<br> <br>**27 to >24.0 ptsGood** The response includes an accurate explanation of the impact of disease on the immune system.<br> <br>**24 to >17.0 ptsFair** The response includes a vague or inaccurate explanation of the impact of disease on the immune system.<br> <br>**17 to >0 ptsPoor** The response includes a vague and inaccurate explanation of the impact of disease on the immune system. | 30 pts |
| This criterion is linked to a Learning OutcomeWritten Expression and Formatting – Paragraph Development and Organization: Paragraphs make clear points that support well-developed ideas, flow logically, and demonstrate continuity of ideas. Sentences are carefully focused—neither long and rambling nor short and lacking substance. Content is supported by current evidence-based sources. | **5 to >4.0 ptsExcellent** Paragraphs and sentences follow writing standards for flow, continuity, and clarity. … Content is supported by current evidence-based sources.<br> <br>**4 to >3.0 ptsGood** Paragraphs and sentences follow writing standards for flow, continuity, and clarity 80% of the time. … Some content is supported by current evidence-based sources.<br> <br>**3 to >2.0 ptsFair** Paragraphs and sentences follow writing standards for flow, continuity, and clarity 60%–79% of the time. … Some content is supported by current evidence-based sources.<br> <br>**2 to >0 ptsPoor** Paragraphs and sentences follow writing standards for flow, continuity, and clarity < 60% of the time. … No content is supported by current evidence-based source. | 5 pts |
| This criterion is linked to a Learning OutcomeWritten Expression and Formatting – English Writing Standards: Correct grammar, mechanics, and proper punctuation | **5 to >4.0 ptsExcellent** Uses correct grammar, spelling, and punctuation with no errors.<br> <br>**4 to >3.0 ptsGood** Contains a few (1 or 2) grammar, spelling, and punctuation errors.<br> <br>**3 to >2.0 ptsFair** Contains several (3 or 4) grammar, spelling, and punctuation errors.<br> <br>**2 to >0 ptsPoor** Contains many (≥ 5) grammar, spelling, and punctuation errors that interfere with the reader’s understanding. | 5 pts |
| This criterion is linked to a Learning OutcomeWritten Expression and Formatting – The paper follows correct APA format for title page, headings, font, spacing, margins, indentations, page numbers, running heads, parenthetical/in-text citations, and reference list. | **5 to >4.0 ptsExcellent** Uses correct APA format with no errors.<br> <br>**4 to >3.0 ptsGood** Contains a few (1 or 2) APA format errors.<br> <br>**3 to >2.0 ptsFair** Contains several (3 or 4) APA format errors.<br> <br>**2 to >0 ptsPoor** Contains many (≥ 5) APA format errors. | 5 pts |
**## INSTRUCTIONSFORCASESTUDY.docx**
INSTRUCTIONS FOR CASE STUDY
An understanding of cells and cell behavior is a critically important component of disease diagnosis and treatment. But some diseases can be complex in nature, with a variety of factors and circumstances impacting their emergence and severity.
Effective disease analysis often requires an understanding that goes beyond isolated cell behavior. Genes, the environments in which cell processes operate, the impact of patient characteristics, and racial and ethnic variables all can have an important impact.
An understanding of the signals and symptoms of alterations in cellular processes is a critical step in the diagnosis and treatment of many diseases. For APRNs, this understanding can also help educate patients and guide them through their treatment plans.
In this Assignment, you examine a case study and analyze the symptoms presented. In 1-2 pages, you will answer the questions provided following the case scenario. You must use current evidence-based resources to support your answers. Follow APA guidelines. Follow the grading rubric.
**To prepare:**
By Day 1 of this week, you will be assigned to a specific case study for this Case Study Assignment. Please see the “Announcements” section of the classroom for your assignment from your Instructor.
**The Assignment**
Develop a 1- to 2-page case study analysis by answering the questions provided following the case scenario.
**Case Study**
Ensure that you follow the rubric closely. When the rubric calls for current, evidence-based sources, this means that they should be within the last 5 years. You should have at least 2 sources cited. The textbook does not count as one of the sources. The prompt is attached as a pdf.
The following should be addressed in your 1-2 pages –
1. Describe the pathophysiology and reason for symptoms.
2. Discuss genetic mutations and risk factors associated with this disorder.
3. Identify racial/ethnic factors that can put patients more at risk. Discuss anything in the patient hx or lifestyle that would increase the potential for the disease process.
Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The sample paper provided at the Walden Writing Center provides an example of those required elements (available at
[https://academicguides.waldenu.edu/writingcenter/templatesLinks to an external site.](https://academicguides.waldenu.edu/writingcenter/templates)). All papers submitted must use this formatting.
| | | |
| — | — | — |
| Develop a 1- to 2-page case study analysis, examining the patient signs and symptoms presented in the case study; discussing the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. | **30 to >27.0 ptsExcellent** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. … The response is supported by evidence and/or research, as appropriate, to support the explanation.<br> <br>**27 to >24.0 ptsGood** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. … The response supported by evidence and/or research, as appropriate, to support the explanation.<br> <br>**24 to >22.0 ptsFair** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis in a manner that is vague or inaccurate. … The response is supported with explanations that are vague or based on inappropriate evidence/research.<br> <br>**22 to >0 ptsPoor** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis in a manner that is vague and inaccurate, or the description is missing. … The response does not include rationales, or the explanations are vague or based on inappropriate or no evidence/research. | 30 pts |
| This criterion is linked to a Learning OutcomeWhat role do genetic mutations play in the development of the disease? | **25 to >22.0 ptsExcellent** The response includes an accurate, complete, detailed, and specific analysis of the genes that may be associated with the development of the disease.<br> <br>**22 to >19.0 ptsGood** The response includes an accurate analysis of the genes that may be associated with the development of the disease.<br> <br>**19 to >17.0 ptsFair** The response includes a vague or inaccurate analysis of the genes that may be associated with the development of the disease.<br> <br>**17 to >0 ptsPoor** The response includes a vague or inaccurate analysis of the genes that may be associated with the development of the disease is missing. | 25 pts |
| This criterion is linked to a Learning OutcomeWhat is the impact of the disease on the immune system? …… How do treatment strategies target the pathophysiological mechanisms of the disease? | **30 to >27.0 ptsExcellent** The response includes an accurate, complete, detailed, and specific explanation of the impact of the disease on the immune system. Response includes an accurate, complete, detailed, and specific explanation of how treatment strategies target the pathophysiological mechanisms of the disease.<br> <br>**27 to >24.0 ptsGood** The response includes an accurate explanation of the impact of disease on the immune system.<br> <br>**24 to >17.0 ptsFair** The response includes a vague or inaccurate explanation of the impact of disease on the immune system.<br> <br>**17 to >0 ptsPoor** The response includes a vague and inaccurate explanation of the impact of disease on the immune system. | 30 pts |
| This criterion is linked to a Learning OutcomeWritten Expression and Formatting – Paragraph Development and Organization: Paragraphs make clear points that support well-developed ideas, flow logically, and demonstrate continuity of ideas. Sentences are carefully focused—neither long and rambling nor short and lacking substance. Content is supported by current evidence-based sources. | **5 to >4.0 ptsExcellent** Paragraphs and sentences follow writing standards for flow, continuity, and clarity. … Content is supported by current evidence-based sources.<br> <br>**4 to >3.0 ptsGood** Paragraphs and sentences follow writing standards for flow, continuity, and clarity 80% of the time. … Some content is supported by current evidence-based sources.<br> <br>**3 to >2.0 ptsFair** Paragraphs and sentences follow writing standards for flow, continuity, and clarity 60%–79% of the time. … Some content is supported by current evidence-based sources.<br> <br>**2 to >0 ptsPoor** Paragraphs and sentences follow writing standards for flow, continuity, and clarity < 60% of the time. … No content is supported by current evidence-based source. | 5 pts |
| This criterion is linked to a Learning OutcomeWritten Expression and Formatting – English Writing Standards: Correct grammar, mechanics, and proper punctuation | **5 to >4.0 ptsExcellent** Uses correct grammar, spelling, and punctuation with no errors.<br> <br>**4 to >3.0 ptsGood** Contains a few (1 or 2) grammar, spelling, and punctuation errors.<br> <br>**3 to >2.0 ptsFair** Contains several (3 or 4) grammar, spelling, and punctuation errors.<br> <br>**2 to >0 ptsPoor** Contains many (≥ 5) grammar, spelling, and punctuation errors that interfere with the reader’s understanding. | 5 pts |
| This criterion is linked to a Learning OutcomeWritten Expression and Formatting – The paper follows correct APA format for title page, headings, font, spacing, margins, indentations, page numbers, running heads, parenthetical/in-text citations, and reference list. | **5 to >4.0 ptsExcellent** Uses correct APA format with no errors.<br> <br>**4 to >3.0 ptsGood** Contains a few (1 or 2) APA format errors.<br> <br>**3 to >2.0 ptsFair** Contains several (3 or 4) APA format errors.<br> <br>**2 to >0 ptsPoor** Contains many (≥ 5) APA format errors. | 5 pts |
**## week2casestudywinter25studentversion.pdf**
Case Study Week 2
Patient Profile
• Name: Sarah L., 32-year-old female
• Occupation: Teacher
• Chief Complaint: “My skin rash keeps getting worse and is really itchy.”
• Onset: 2 weeks
• Past Medical History: Mild seasonal allergies, no chronic illnesses
• Medications: None
• Social History: Lives with two cats, recently moved into an older home; no recent
travel
• Family History: Mother—eczema; father—type 2 diabetes
History of Present Illness
The patient reports a progressively worsening itchy rash on the palms, elbows, and
behind the knees. Initially mild, the rash is now erythematous, dry, and starting to crack.
She notes increased itching at night.
Denies new soaps or detergents, but admits to using a new scented body lotion. Stress
levels have been high due to work.
Physical Examination
• Vitals:
o Temp 98.4°F
o HR 78 bpm
o BP 118/72 mmHg
o RR 14
• Skin Exam:
o Erythematous plaques with silver-white scale on elbows
o Lichenification in popliteal and antecubital fossae
o Small fissures on palmar surfaces
o No drainage, no signs of infection
• Nails:
o Mild pitting on fingernails
• Other Systems: Normal
Sample Lab Studies
Note: Skin disorders are often clinical diagnoses, but labs help rule out infection/allergy or
support alternatives.
CBC
Test Result Normal Range
WBC 7.0 x10³/µL 4.5–11
Hemoglobin 13.4 g/dL 12–16
Platelets 280 x10³/µL 150–400
Eosinophils 7% (high) 0–5
ESR
Test Result Normal
ESR 18 mm/hr 0–20 mm/hr
CRP
Test Result Normal
CRP 0.9 mg/dL <1
IgE Level
Test Result Normal
IgE 250 IU/mL 0–100 IU/mL
Skin Scraping (KOH prep)
• Negative for hyphae
**## INSTRUCTIONSFORCASESTUDY.docx**
INSTRUCTIONS FOR CASE STUDY
An understanding of cells and cell behavior is a critically important component of disease diagnosis and treatment. But some diseases can be complex in nature, with a variety of factors and circumstances impacting their emergence and severity.
Effective disease analysis often requires an understanding that goes beyond isolated cell behavior. Genes, the environments in which cell processes operate, the impact of patient characteristics, and racial and ethnic variables all can have an important impact.
An understanding of the signals and symptoms of alterations in cellular processes is a critical step in the diagnosis and treatment of many diseases. For APRNs, this understanding can also help educate patients and guide them through their treatment plans.
In this Assignment, you examine a case study and analyze the symptoms presented. In 1-2 pages, you will answer the questions provided following the case scenario. You must use current evidence-based resources to support your answers. Follow APA guidelines. Follow the grading rubric.
**To prepare:**
By Day 1 of this week, you will be assigned to a specific case study for this Case Study Assignment. Please see the “Announcements” section of the classroom for your assignment from your Instructor.
**The Assignment**
Develop a 1- to 2-page case study analysis by answering the questions provided following the case scenario.
**Case Study**
Ensure that you follow the rubric closely. When the rubric calls for current, evidence-based sources, this means that they should be within the last 5 years. You should have at least 2 sources cited. The textbook does not count as one of the sources. The prompt is attached as a pdf.
The following should be addressed in your 1-2 pages –
1. Describe the pathophysiology and reason for symptoms.
2. Discuss genetic mutations and risk factors associated with this disorder.
3. Identify racial/ethnic factors that can put patients more at risk. Discuss anything in the patient hx or lifestyle that would increase the potential for the disease process.
Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The sample paper provided at the Walden Writing Center provides an example of those required elements (available at
[https://academicguides.waldenu.edu/writingcenter/templatesLinks to an external site.](https://academicguides.waldenu.edu/writingcenter/templates)). All papers submitted must use this formatting.
| | | |
| — | — | — |
| Develop a 1- to 2-page case study analysis, examining the patient signs and symptoms presented in the case study; discussing the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. | **30 to >27.0 ptsExcellent** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. … The response is supported by evidence and/or research, as appropriate, to support the explanation.<br> <br>**27 to >24.0 ptsGood** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. … The response supported by evidence and/or research, as appropriate, to support the explanation.<br> <br>**24 to >22.0 ptsFair** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis in a manner that is vague or inaccurate. … The response is supported with explanations that are vague or based on inappropriate evidence/research.<br> <br>**22 to >0 ptsPoor** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis in a manner that is vague and inaccurate, or the description is missing. … The response does not include rationales, or the explanations are vague or based on inappropriate or no evidence/research. | 30 pts |
| This criterion is linked to a Learning OutcomeWhat role do genetic mutations play in the development of the disease? | **25 to >22.0 ptsExcellent** The response includes an accurate, complete, detailed, and specific analysis of the genes that may be associated with the development of the disease.<br> <br>**22 to >19.0 ptsGood** The response includes an accurate analysis of the genes that may be associated with the development of the disease.<br> <br>**19 to >17.0 ptsFair** The response includes a vague or inaccurate analysis of the genes that may be associated with the development of the disease.<br> <br>**17 to >0 ptsPoor** The response includes a vague or inaccurate analysis of the genes that may be associated with the development of the disease is missing. | 25 pts |
| This criterion is linked to a Learning OutcomeWhat is the impact of the disease on the immune system? …… How do treatment strategies target the pathophysiological mechanisms of the disease? | **30 to >27.0 ptsExcellent** The response includes an accurate, complete, detailed, and specific explanation of the impact of the disease on the immune system. Response includes an accurate, complete, detailed, and specific explanation of how treatment strategies target the pathophysiological mechanisms of the disease.<br> <br>**27 to >24.0 ptsGood** The response includes an accurate explanation of the impact of disease on the immune system.<br> <br>**24 to >17.0 ptsFair** The response includes a vague or inaccurate explanation of the impact of disease on the immune system.<br> <br>**17 to >0 ptsPoor** The response includes a vague and inaccurate explanation of the impact of disease on the immune system. | 30 pts |
| This criterion is linked to a Learning OutcomeWritten Expression and Formatting – Paragraph Development and Organization: Paragraphs make clear points that support well-developed ideas, flow logically, and demonstrate continuity of ideas. Sentences are carefully focused—neither long and rambling nor short and lacking substance. Content is supported by current evidence-based sources. | **5 to >4.0 ptsExcellent** Paragraphs and sentences follow writing standards for flow, continuity, and clarity. … Content is supported by current evidence-based sources.<br> <br>**4 to >3.0 ptsGood** Paragraphs and sentences follow writing standards for flow, continuity, and clarity 80% of the time. … Some content is supported by current evidence-based sources.<br> <br>**3 to >2.0 ptsFair** Paragraphs and sentences follow writing standards for flow, continuity, and clarity 60%–79% of the time. … Some content is supported by current evidence-based sources.<br> <br>**2 to >0 ptsPoor** Paragraphs and sentences follow writing standards for flow, continuity, and clarity < 60% of the time. … No content is supported by current evidence-based source. | 5 pts |
| This criterion is linked to a Learning OutcomeWritten Expression and Formatting – English Writing Standards: Correct grammar, mechanics, and proper punctuation | **5 to >4.0 ptsExcellent** Uses correct grammar, spelling, and punctuation with no errors.<br> <br>**4 to >3.0 ptsGood** Contains a few (1 or 2) grammar, spelling, and punctuation errors.<br> <br>**3 to >2.0 ptsFair** Contains several (3 or 4) grammar, spelling, and punctuation errors.<br> <br>**2 to >0 ptsPoor** Contains many (≥ 5) grammar, spelling, and punctuation errors that interfere with the reader’s understanding. | 5 pts |
| This criterion is linked to a Learning OutcomeWritten Expression and Formatting – The paper follows correct APA format for title page, headings, font, spacing, margins, indentations, page numbers, running heads, parenthetical/in-text citations, and reference list. | **5 to >4.0 ptsExcellent** Uses correct APA format with no errors.<br> <br>**4 to >3.0 ptsGood** Contains a few (1 or 2) APA format errors.<br> <br>**3 to >2.0 ptsFair** Contains several (3 or 4) APA format errors.<br> <br>**2 to >0 ptsPoor** Contains many (≥ 5) APA format errors. | 5 pts |
**## week2casestudywinter25studentversion.pdf**
Case Study Week 2
Patient Profile
• Name: Sarah L., 32-year-old female
• Occupation: Teacher
• Chief Complaint: “My skin rash keeps getting worse and is really itchy.”
• Onset: 2 weeks
• Past Medical History: Mild seasonal allergies, no chronic illnesses
• Medications: None
• Social History: Lives with two cats, recently moved into an older home; no recent
travel
• Family History: Mother—eczema; father—type 2 diabetes
History of Present Illness
The patient reports a progressively worsening itchy rash on the palms, elbows, and
behind the knees. Initially mild, the rash is now erythematous, dry, and starting to crack.
She notes increased itching at night.
Denies new soaps or detergents, but admits to using a new scented body lotion. Stress
levels have been high due to work.
Physical Examination
• Vitals:
o Temp 98.4°F
o HR 78 bpm
o BP 118/72 mmHg
o RR 14
• Skin Exam:
o Erythematous plaques with silver-white scale on elbows
o Lichenification in popliteal and antecubital fossae
o Small fissures on palmar surfaces
o No drainage, no signs of infection
• Nails:
o Mild pitting on fingernails
• Other Systems: Normal
Sample Lab Studies
Note: Skin disorders are often clinical diagnoses, but labs help rule out infection/allergy or
support alternatives.
CBC
Test Result Normal Range
WBC 7.0 x10³/µL 4.5–11
Hemoglobin 13.4 g/dL 12–16
Platelets 280 x10³/µL 150–400
Eosinophils 7% (high) 0–5
ESR
Test Result Normal
ESR 18 mm/hr 0–20 mm/hr
CRP
Test Result Normal
CRP 0.9 mg/dL <1
IgE Level
Test Result Normal
IgE 250 IU/mL 0–100 IU/mL
Skin Scraping (KOH prep)
• Negative for hyphae
**## INSTRUCTIONSFORCASESTUDY.docx**
INSTRUCTIONS FOR CASE STUDY
An understanding of cells and cell behavior is a critically important component of disease diagnosis and treatment. But some diseases can be complex in nature, with a variety of factors and circumstances impacting their emergence and severity.
Effective disease analysis often requires an understanding that goes beyond isolated cell behavior. Genes, the environments in which cell processes operate, the impact of patient characteristics, and racial and ethnic variables all can have an important impact.
An understanding of the signals and symptoms of alterations in cellular processes is a critical step in the diagnosis and treatment of many diseases. For APRNs, this understanding can also help educate patients and guide them through their treatment plans.
In this Assignment, you examine a case study and analyze the symptoms presented. In 1-2 pages, you will answer the questions provided following the case scenario. You must use current evidence-based resources to support your answers. Follow APA guidelines. Follow the grading rubric.
**To prepare:**
By Day 1 of this week, you will be assigned to a specific case study for this Case Study Assignment. Please see the “Announcements” section of the classroom for your assignment from your Instructor.
**The Assignment**
Develop a 1- to 2-page case study analysis by answering the questions provided following the case scenario.
**Case Study**
Ensure that you follow the rubric closely. When the rubric calls for current, evidence-based sources, this means that they should be within the last 5 years. You should have at least 2 sources cited. The textbook does not count as one of the sources. The prompt is attached as a pdf.
The following should be addressed in your 1-2 pages –
1. Describe the pathophysiology and reason for symptoms.
2. Discuss genetic mutations and risk factors associated with this disorder.
3. Identify racial/ethnic factors that can put patients more at risk. Discuss anything in the patient hx or lifestyle that would increase the potential for the disease process.
Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The sample paper provided at the Walden Writing Center provides an example of those required elements (available at
[https://academicguides.waldenu.edu/writingcenter/templatesLinks to an external site.](https://academicguides.waldenu.edu/writingcenter/templates)). All papers submitted must use this formatting.
| | | |
| — | — | — |
| Develop a 1- to 2-page case study analysis, examining the patient signs and symptoms presented in the case study; discussing the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. | **30 to >27.0 ptsExcellent** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. … The response is supported by evidence and/or research, as appropriate, to support the explanation.<br> <br>**27 to >24.0 ptsGood** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis. … The response supported by evidence and/or research, as appropriate, to support the explanation.<br> <br>**24 to >22.0 ptsFair** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis in a manner that is vague or inaccurate. … The response is supported with explanations that are vague or based on inappropriate evidence/research.<br> <br>**22 to >0 ptsPoor** The response discusses the primary cellular pathophysiological processes, and the significance for symptom development and diagnosis in a manner that is vague and inaccurate, or the description is missing. … The response does not include rationales, or the explanations are vague or based on inappropriate or no evidence/research. | 30 pts |
| This criterion is linked to a Learning OutcomeWhat role do genetic mutations play in the development of the disease? | **25 to >22.0 ptsExcellent** The response includes an accurate, complete, detailed, and specific analysis of the genes that may be associated with the development of the disease.<br> <br>**22 to >19.0 ptsGood** The response includes an accurate analysis of the genes that may be associated with the development of the disease.<br> <br>**19 to >17.0 ptsFair** The response includes a vague or inaccurate analysis of the genes that may be associated with the development of the disease.<br> <br>**17 to >0 ptsPoor** The response includes a vague or inaccurate analysis of the genes that may be associated with the development of the disease is missing. | 25 pts |
| This criterion is linked to a Learning OutcomeWhat is the impact of the disease on the immune system? …… How do treatment strategies target the pathophysiological mechanisms of the disease? | **30 to >27.0 ptsExcellent** The response includes an accurate, complete, detailed, and specific explanation of the impact of the disease on the immune system. Response includes an accurate, complete, detailed, and specific explanation of how treatment strategies target the pathophysiological mechanisms of the disease.<br> <br>**27 to >24.0 ptsGood** The response includes an accurate explanation of the impact of disease on the immune system.<br> <br>**24 to >17.0 ptsFair** The response includes a vague or inaccurate explanation of the impact of disease on the immune system.<br> <br>**17 to >0 ptsPoor** The response includes a vague and inaccurate explanation of the impact of disease on the immune system. | 30 pts |
| This criterion is linked to a Learning OutcomeWritten Expression and Formatting – Paragraph Development and Organization: Paragraphs make clear points that support well-developed ideas, flow logically, and demonstrate continuity of ideas. Sentences are carefully focused—neither long and rambling nor short and lacking substance. Content is supported by current evidence-based sources. | **5 to >4.0 ptsExcellent** Paragraphs and sentences follow writing standards for flow, continuity, and clarity. … Content is supported by current evidence-based sources.<br> <br>**4 to >3.0 ptsGood** Paragraphs and sentences follow writing standards for flow, continuity, and clarity 80% of the time. … Some content is supported by current evidence-based sources.<br> <br>**3 to >2.0 ptsFair** Paragraphs and sentences follow writing standards for flow, continuity, and clarity 60%–79% of the time. … Some content is supported by current evidence-based sources.<br> <br>**2 to >0 ptsPoor** Paragraphs and sentences follow writing standards for flow, continuity, and clarity < 60% of the time. … No content is supported by current evidence-based source. | 5 pts |
| This criterion is linked to a Learning OutcomeWritten Expression and Formatting – English Writing Standards: Correct grammar, mechanics, and proper punctuation | **5 to >4.0 ptsExcellent** Uses correct grammar, spelling, and punctuation with no errors.<br> <br>**4 to >3.0 ptsGood** Contains a few (1 or 2) grammar, spelling, and punctuation errors.<br> <br>**3 to >2.0 ptsFair** Contains several (3 or 4) grammar, spelling, and punctuation errors.<br> <br>**2 to >0 ptsPoor** Contains many (≥ 5) grammar, spelling, and punctuation errors that interfere with the reader’s understanding. | 5 pts |
| This criterion is linked to a Learning OutcomeWritten Expression and Formatting – The paper follows correct APA format for title page, headings, font, spacing, margins, indentations, page numbers, running heads, parenthetical/in-text citations, and reference list. | **5 to >4.0 ptsExcellent** Uses correct APA format with no errors.<br> <br>**4 to >3.0 ptsGood** Contains a few (1 or 2) APA format errors.<br> <br>**3 to >2.0 ptsFair** Contains several (3 or 4) APA format errors.<br> <br>**2 to >0 ptsPoor** Contains many (≥ 5) APA format errors. | 5 pts |
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